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Newly Discovered Sperm Movement Could Help Diagnose, Treat Male Infertility

Scientists at The University of Toledo discovered new movement in sperm that provides innovative avenues for diagnostics and therapeutic strategies for male infertility.

The research published in Nature Communications finds that the atypical centriole in the sperm neck acts as a transmission system that controls twitching in the head of the sperm, mechanically synchronizing the sperm tail movement to the new head movement.

The centriole has historically been considered a rigid structure that acts like a shock absorber.

Ph.D. candidate Sushil Khanal, left, and Dr. Tomer Avidor-Reiss, professor of biological sciences, pull cryopreserved semen samples out of a liquid nitrogen tank that is kept at -196 degrees celsius.

“We think the atypical centriole in the sperm’s neck is an evolutionary innovation whose function is to make your sperm move better,” said Dr. Tomer Avidor-Reiss, professor of biological sciences in the UToledo College of Natural Sciences and Mathematics. “Reproductive success depends on the ability of sperm to swim through female reproductive tract barriers while out-competing their rivals to fertilize the egg.”

The study led by Ph.D. candidate Sushil Khanal builds upon the lab’s previous groundbreaking discovery in human sperm that changed the dogma in reproductive biology: A father donates not one but two centrioles through the sperm during fertilization, and the newly discovered sperm structure called the atypical centriole may contribute to infertility, miscarriages and birth defects.

“Together, these studies call for a revision in our understanding of sperm centrioles both in sperm movement and in the early embryo,” Avidor-Reiss said.

Avidor-Reiss believes this discovery can open the door to new possibilities to help families understand why they may be having trouble getting pregnant.

If the head and tail of the sperm aren’t moving together, the sperm isn’t going to move efficiently enough to get to the egg.

“If the centriole is defective, this coupling between the sperm tail and head is going to be defective,” Avidor-Reiss said. “In a patient when we don’t know what is wrong, potentially we can look at the way the sperm’s tail moves and reverse engineer it to determine centriole functionality to determine couple’s infertility.”

He also said finding this movement can be used in the future to predict which sperm have a good centriole that can support life.

“Right now, people don’t know what to fix,” Avidor-Reiss said. “We can pinpoint the problem. This knowledge allows us to identify a subgroup of infertile men that was not revealed before.”

The new research shows that in the sperm of mammals there is a cascade of internal sliding formations in the neck’s atypical distal centriole, typical proximal centriole and surrounding material that links tail beating with asymmetric head kinking.

Using a STORM immunofluorescent microscope in the UToledo Instrumentation Center, the researchers were able to show the left and right side of the atypical centriole move about 300 nanometers relative to each other. Though it’s a small number, it marks dramatic movement in a cell considering the average protein diameter is five nanometers.

Ph.D. student Luke Achinger, who recently graduated from UToledo with a bachelor’s degree in biology, sang bass in the University’s premier choral ensemble as an undergraduate and penned lyrics about his lab’s new discovery, explaining how the new movement works in a song called “Twitch, Roll and Yaw.”

“We love to promote science and art, and in this case, we are showing that the sperm beats in unity. The head of the sperm is not isolated from the tail. The neck including the atypical and typical centrioles may act as a morphological computer, or sperm brain, that coordinates the sperm movement,” Avidor-Reiss said.

“The song is a creative way to understand a big change. The centriole always looked the same over the last billion years. It’s one of most conservative structures in the cell. We found something different that functions in the opposite manner, evolving from a shock absorber to a transmission system.”

This study was an international collaboration with Dr. Tzviya Zeev-Ben-Mordehai’s lab at Utrecht University in the Netherlands, which performed state-of-the-art cryo-electron microscopy of the sperm neck, and Hermes Bloomfield-Gadêlha at the University of Bristol in the United Kingdom, who performed mathematical and waveform analysis.


Build-A-Trust Bowl-A-Thon Returns June 26 to Bring Community Together

The Build-A-Trust Bowl-A-Thon, a single-day event designed to bring children and teens together with local police, firefighters and military personnel, returns Saturday, June 26, at New Glass Bowl Lanes, 5133 Telegraph Road in Toledo.

Established in 2015 by George W. Hayes Jr., an electrician at The University of Toledo, the event brings community members together to break down barriers and establish mutual respect.

The bowl-a-thon runs from noon until 3 p.m. All youth 17 and younger bowl for free, courtesy of JCILH Inc., which operates a number of local McDonald’s restaurants.

Those 18 and older can bowl three games for $5 per person. Shoes are included.

“It’s a one-day event with kids, cops, firefighters and some military coming together for a few hours just to mingle, bowl, have fun and not to be afraid of each other,” Hayes said. “The intent is to build trust between men and women in uniform and everyone else so that we all realize that we are just people, regardless of who you are or what you are.

“It’s a fun event that’s very much needed. Regardless of where you are from, you are invited.”


UToledo to Host Virtual Filmmakers Workshop for Teens July 19-30

The University of Toledo Department of Theatre and Film will host a 100% online summer film camp for teens, ages 14-18, interested in learning the basics of filmmaking.

Scheduled from Monday, July 19, through Friday, July 30, the Virtual Filmmaker Summer Film Intensive is a two-week virtual filmmaking summer camp for teens looking to grow their narrative video-making skills. The camp will feature live, online class times and daily assignments, and the instructor, Quincy Joyner, assistant lecturer of theatre and film, will guide and mentor students every step of the way.

Upon successful completion of the camp, participants will be able to:

  • Articulate the components of story, character and narrative, and the effectiveness of communicating visually;
  • Conceive, design, and communicate a story cinematically employing practical filmmaking techniques; and
  • Demonstrate production etiquette and communication necessary to collaboratively produce a film.

The workshop will include:

  • Short script writing
  • Character development
  • Cinematography essentials
  • Practical lighting

The registration deadline for the Virtual Filmmaker Summer Film Intensive is Monday, July 5.

The camp fee is $400 — a $50 non-refundable registration fee due at signup and the $350 camp fee due by July 5 — which covers all materials needed for the workshop.

For more information, visit the Virtual Filmmaker Summer Film Intensive website, or to register, the camp’s form is available online.


USDA Awards UToledo $500,000 for Fertility Research to Optimize Production in Cattle Industry

Every time a dairy cow is bred and fails to become pregnant, a farmer loses a month of profits on the cow’s milk. If it grows to two months, that’s a 20% loss in profit.

“Cows and bulls can have suboptimal fertility, just like humans,” said Dr. Tomer Avidor-Reiss, professor of biological sciences at The University of Toledo. “In the U.S. today, the average dairy cow takes three tries to become pregnant, being bred once each ovulation or estrous cycle.”

The UToledo scientist is now using his advancements made in human fertility research to help farmers reduce their costs for dairy production.

The U.S. Department of Agriculture awarded Avidor-Reiss $500,000 to develop tools and methods for selecting bulls with superior fertility by building upon his groundbreaking discovery in human sperm that changed the dogma in reproductive biology: an atypical centriole.

Dr. Tomer Avidor-Reiss

Several years ago, he found that a father donates not one but two centrioles through the sperm during fertilization, and the newly discovered sperm structure may contribute to infertility, miscarriages and birth defects.

“The beautiful thing about investigating and developing centriolar biomarkers for bull sperm is that it could help us with our human male reproductive research,” Avidor-Reiss said. “And the Council on Dairy Cattle Breeding, or CDCB, has an incredible database on bull fertility — it’s a robust, publicly available statistical report on fertility because the farmer reports whether each mating of a bull and cow resulted in a pregnancy. There is no report like this on any other species.”

The CDCB’s database for Sire Conception Rate, which originated under USDA’s guidance, was created to help dairy farmers “grade” the fertility of bull sperm.

The three-year project for the USDA continues the UToledo scientist’s collaboration with Select Sires Inc., an Ohio company that sells cryopreserved bull sperm for artificial insemination.

“The cattle genetics industries are constantly searching for ways to better serve dairy and beef producers around the world,” said Dr. Bo Harstine, director of research at Select Sires Inc. “Dr. Avidor-Reiss’s research examining the role that a sperm cell’s centrioles have in fertility could have major implications on our understanding of cattle breeding. As an Ohio-based biotechnology cooperative, Select Sires Inc. is proud to be partnering with The University of Toledo and Dr. Avidor-Reiss to bridge this research from the laboratory to real-world applications.”

Avidor-Reiss’s laboratory developed a quantitative method to determine sperm centriole quality, and preliminary results show that sub-fertile bulls have lower-quality centrioles.

“The University of Toledo’s efforts to attract federally supported research are far-reaching and have an economic impact on our region,” Congresswoman Marcy Kaptur said. “With USDA support, Dr. Tomer Avidor-Reiss will bolster knowledge about animal fertility and, in turn, the economic outlook for the dairy and cattle industry in northern Ohio.”


NASA Awards UToledo Engineers Grant to Enhance Solar Power Conversion for Mars, Moon Missions

A team of engineers in The University of Toledo College of Engineering is working with NASA’s Jet Propulsion Laboratory to more reliably power spacecraft using the sun’s energy on future missions to Mars and the moon.

The electricity generated by solar panels aboard a spacecraft is used to provide power for a number of systems, including propulsion and navigation.

Before the solar-derived electricity is integrated with those systems, it must first pass through an intermediary circuit, or a “power converter,” that conditions the electricity coming from the solar panel so that it is compatible with the propulsion and navigation systems.

However, cosmic rays that float in space and contain ions are disrupting the performance of this power converter, causing radiation-related failures.

Dr. Raghav Khanna, left, and Dr. Daniel Georgiev

NASA awarded Dr. Daniel Georgiev and Dr. Raghav Khanna, both associate professors in the Department of Electrical Engineering and Computer Science, a three-year, $240,000 grant to investigate how to make the power conversion circuitry more resilient and tolerant to space-related radiation, which degrades its performance and results in power loss and system downtime.

“We are honored and excited that our research will contribute to NASA’s goal of putting more exploratory devices and electrical power on Mars,” said Khanna, who has done prior work with NASA on power electronics and semiconductor studies. “Ever since I was a kid, it has been a dream to work with NASA and maybe someday walk on the moon like Neil Armstrong.”

Using a solar array simulator in their laboratory, high-speed precision computers and guidance from NASA, Georgiev and Khanna are modeling why the circuits are failing.

The simulator emulates the characteristics of solar arrays used in space and provides power to a power converter circuit built by the UToledo team and NASA engineers.

“We’re analyzing how the radiation penetrates the circuit and what causes these devices to degrade,” Georgiev said.

At the same time, the team will study the degradation mechanisms in a particular application relevant to NASA by developing a power converter that allows the solar panels aboard NASA spacecraft to continuously extract maximum power from available sunlight.

“As the spacecraft is moving around and goes behind a celestial body, maximum available power tends to change rapidly,” Khanna said. “On the moon, lunar dust can also obscure the panel from the sun, leading to rapid changes in available power. Whether in deep space or in lunar missions, we need to develop a control algorithm to make sure we can always extract maximum available power from solar panels at a much greater efficiency while exhibiting improved radiation tolerance, allowing uninterrupted exploration.”


New Dean Selected to Lead UToledo College of Natural Sciences and Mathematics

An astronomer and program director at a major federal funding agency will join The University of Toledo as the leader of the College of Natural Sciences and Mathematics effective Aug. 2.

Dr. Marc Seigar comes to UToledo from the National Science Foundation where he is a rotating program director in the Division of Astronomical Sciences and from the University of Minnesota at Duluth where he is a professor of physics and astronomy. He also has served as head of the Department of Physics and Astronomy and associate dean of the Swenson College of Science and Engineering at the University of Minnesota at Duluth.

“We are very pleased that Dr. Marc Seigar will be joining us as the next dean of the College of Natural Sciences and Mathematics,” said Dr. Karen Bjorkman, provost and executive vice president for academic affairs. “With his familiarity with the National Science Foundation, his knowledge of interdisciplinary research and education, his research and administrative experience, and his collaborative approach, he will provide great leadership to continue to move the college forward into the future. We look forward to welcoming him to UToledo.”

“The University of Toledo College of Natural Sciences and Mathematics is home to world-class faculty doing great things in a wide variety of fields ranging from sustainable technology and photovoltaics to water quality and astronomy,” Seigar said. “It’s going in a strong direction, and I want to be there to help for the future.”

During his one-year rotation at the NSF, Seigar oversees grant panels in the Research Experiences for Undergraduates program, the Graduate Student Research Fellowship program, the Astronomy and Astrophysics Grants program, and the new ASCEND postdoctoral fellowship program. His portfolio of awarded grants totals more than $30 million that has gone to researchers across the country.

“I have unique experience into the kinds of cross-disciplinary research that a major federal granting agency is likely to fund,” Seigar said. “Plus, with the new degree program in data science that started recently in the UToledo College of Natural Sciences and Mathematics, I think there’s faculty who can tap into the NSF’s Computational and Data-Enabled Science and Engineering program, which I don’t think a lot of people know about.”

As an astronomer, his research is focused on the structure, morphology and dynamics of galaxies and their dark matter halos and the nature of the dark matter particle.

He has been involved in research projects that have received more than $7 million in grants, one of which was a $3.7 million educational grant specifically for underrepresented minority students in STEM. The project called the North Star STEM Alliance is an alliance of four- and two-year colleges in Minnesota.

“There is a job for you if you get a STEM degree,” Seigar said. “In most states across the country, they are projecting tens of thousands of jobs are going unfilled because we don’t have enough graduates coming out with STEM degrees. I believe bridge programs are critical to student success, especially for underrepresented students. We need to start reaching out to students in middle school, before they reach 7th or 8th grade. We’re facing big issues as a society, especially in topics related to the environment and sustainable technologies. We need to equip the next generation to continue the search for solutions.”

Prior to the University of Minnesota, Seigar served as associate chair of the Department of Physics and Astronomy at the University of Arkansas at Little Rock, where he also previously worked as the department’s director of graduate studies.

He also has held astronomy positions at the University of California Irvine, the U.K. Infrared Telescope in Hawaii, and the Astronomical Observatory at the University of Ghent in Belgium. He has held visiting or adjunct appointments at the Center for Space and Planetary Science at the University of Arkansas at Fayetteville, the Observatories of the Carnegie Institution for Science in Pasadena, Calif., the University of Hawaii at Hilo, and the Space Telescope Science Institute in Baltimore.

Seigar earned his Ph.D. in astrophysics from the Liverpool Astrophysics Research Institute and his bachelor’s degree in physics from Imperial College.

Originally from London, Seigar moved to the United States in 2001. He and his wife Colleen have two sons: Andrew, 10, and David, 12.

Bjorkman thanked Dr. John Plenefisch for his excellent leadership while serving as interim dean since January 2019. He will return to the position of associate dean of the College of Natural Sciences and Mathematics.


Professor’s Award-Winning Poetry Unmasks ‘Plunder’ of Asian American Bodies, Korean History

Dr. Joey Kim’s first book of poetry has poetic timing as Asian Americans have been targets of violence across the U.S. during the COVID-19 pandemic.

Venturing through Korean history, the feminine body, U.S. foreign policy and coming-of-age in midwestern America, Kim’s “Body Facts” will be released by Diode Editions on Tuesday, June 15, after winning an international publication contest last year.

Dr. Joey Kim

“It’s urgent,” said Kim, assistant professor in the Department of English Language and Literature in The University of Toledo College of Arts and Letters. “Asians have been here in the U.S. since the 1500s, but it hasn’t been until recently that there has been a national reckoning of Asian Americans as not perpetual foreigners.”

Writing the poems over the last 13 years was therapeutic for the Asian American scholar.

Using tweets from former President Donald Trump and comments from childhood neighbors and classmates, Kim found a place to unpack her identity, the double consciousness of growing up in two cultures at once, the accrual of racist encounters, and the historical and generational impacts of war and colonization.

“My collection is able to put a face and a name and a story to these voices,” Kim said. “These voices speak back to a history of Asian American representations that have largely been essentializing and stereotypical.”

Kim grew up in Ohio as the daughter of doctors, who were immigrants from South Korea, and speaking Korean as her first language.

She wanted to be a writer, not a doctor, while white neighbors and classmates wanted to know where she was really from.

From the poem “Orientalism,” Kim quotes childhood classmates on the school bus:

“Where are you really really from?

Haha, you eat dog and monkey brain!

Why does your lunch smell like feet?

Your face is flat like a plate! Ching-chong Donkey Kong!”

How do I get to where I really came from, if I’ve only ever been here, in Ohio?

In the same poem, she quotes Trump’s response after being asked by a reporter whether he plans to attack North Korea.

“We’ll see” —

If this land is a land for me, and the ones like me who can only spectate in

spectral horror — while he tweets us into oblivion.

“My poems speak to psychological effects of growing up in places where you always have to try to maneuver these different cultures,” Kim said.

“Plunder,” one of the poems in the collection, has already been nominated for a Pushcart Prize, a prestigious national literary award given out annually since 1976.  Kim also won first place in the Art Commission’s 2020 Merit Awards.

“The inspiration behind ‘Plunder’ is the dispossession of Korean land and bodies during the Japanese occupation and Korean war, which is still technically ongoing,” Kim said. “The poem interlaces the speaker’s childhood memories, American plastic surgery experimentation on Korean subjects, and the fetishization of women’s faces and bodies as objects to be modified and plundered.”

In her collection, Kim writes from different perspectives of the body — body as human and the pressures people place on their bodies, or body as land, the Korean Peninsula, to be exact.

“We are still occupied by U.S. forces and in the shadow of American imperialism,” Kim said. “In one of the poems, I talk about the Trump era of Korean discourse and our sense, as Korean Americans, of feeling stereotyped with North Korean dictatorship.”

The poetry expands beyond “slurs,” “slit eyes” and foreign policy. When Kim talks about the body as a site of celebration and trauma, she also is reflecting on the brain hemorrhage and traumatic brain injury she suffered while skateboarding in May 2015.

She had only been skateboarding for a couple months while in graduate school at Ohio State University before she became a Ph.D. candidate when she took off her helmet and tried to go down a hill at a skatepark by herself.

“I was in the ICU for 11 days. At first, the doctors told my family I most likely wouldn’t be able to walk or talk in the same way again,” Kim said. “Because of my youth, I had, in the words of my neurosurgeon, a ‘miraculous’ recovery. My hearing is back, too.”

“Our bodies hold and hide our histories,” said Min Jin Lee, author of “Free Food for Millionaires” and “Pachinko,” a National Book Award Finalist. “Line by line, Joey Kim breaks us open to expose our yearnings, secrets, and untold treasures, saving us from our own fortress of history, propriety, and shame. Kim’s ‘Body Facts’ is our needed revelation.”

“Kim’s work, from multiple angles, portrays the ways in which peace and beauty are forced to find new escapes from tyrants and the fallouts of their power,” said Marcus Jackson, author of “Pardon My Heart,” the 2019 Ohioana Book Award winner for poetry. “Kim admirably illustrates present and historical threats, all while rendering the ageless brilliance of family and spirit.”

 

 


U.S. Army Corps of Engineers Awards UToledo $1.4 Million to Develop New Techniques to Combat Toxic Algae

The U.S. Army Corps of Engineers awarded researchers at The University of Toledo $1.4 million to develop enhanced technology for early detection and management of harmful algal blooms, Lake Erie’s environmental menace and a worldwide problem.

Dr. Youngwoo Seo, professor of civil and environmental engineering and chemical engineering in the UToledo College of Engineering, leads the three-year project to improve water quality from the source to the tap.

Dr. Thomas Bridgeman, Dr. Youngwoo Seo and Dr. Dae-Wook Kang

Some of the technology and techniques being tested by UToledo are new to water treatment plants in the western hemisphere. Water treatment plants in northwest Ohio are collaborating on the project along with the U.S. Environmental Protection Agency, Ohio State University and Sepro Inc. Participating municipal water treatment plants include Toledo, Bowling Green, Celina and Oregon.

The project features two different parts working together:

  • Advanced monitoring sensors and molecular genetic analyses to enhance early harmful algal bloom detection and real-time condition diagnostic capability; and
  • Nature-inspired biological treatment methods coupled with algaecides to attack cyanobacteria and degrade toxins produced by cyanobacteria.

“We are excited that our proposed method and new techniques can make real changes for water utilities and the water quality in the lake,” Seo said. “It has great potential to be a more sustainable way to handle the cyanobacteria and their toxins.”

“Harmful algal blooms are a growing and costly problem affecting the nation,” said Dr. Jen Seiter-Moser, the U.S. Army Engineer Research and Development Center’s acting technical director for civil works, environmental engineering and sciences. “At ERDC, we benefit from collaboration with other federal, academic and industry partners. We’re looking forward to working with our UToledo partners to find solutions that can be applied regionally and then scaled up for nationwide application.”

Dr. Thomas Bridgeman, professor of ecology in the UToledo College of Natural Sciences and Mathematics and director of the UToledo Lake Erie Center, will lead the monitoring. First, he will test new instruments called fluoroprobes in the lab using algal cultures. The second stage will be to use them in Lake Erie, and finally work with water treatment plants to incorporate these instruments as part of their source water monitoring.

The sensors can detect the health, or physiological condition, of the cyanobacteria — whether the cyanobacterial cells are becoming fragile and leaky, releasing their toxins into the water — along with the concentration of cyanobacteria and how blooms react to water treatment chemicals.

“These monitoring sensors made by the German company bbe Moldaenke are capable of easily detecting when cyanobacterial cells are starting to rupture, which could be a powerful tool for water utility managers to respond to and minimize toxin release,” Bridgeman said.

Dr. Dae-Wook Kang, assistant professor of civil and environmental engineering in the UToledo College of Engineering, will lead a molecular approach to develop a robust detection method. He will obtain rich microbial DNA, RNA and metabolomic information from samples, which can be an indicator of cell metabolism, and try to better identify the biomarker for the harmful algal bloom.

“Harmful algal blooms are outcomes of a complex network between cyanobacteria and neighboring competitors such as cyanophages and eukaryotes. By integrating these dynamic microbiome data together with sensor and water chemical data, we aim to develop an early and rapid detection tool of harmful algal blooms,” Kang said.

“In the lake we have harmful algal blooms but also other bacteria that interact with each other,” Seo said. “Sometimes cyanobacteria don’t produce high concentrations of toxins even when the bloom is large. Sometimes we have a small bloom, but have high concentrations of toxins.”

Kang is using molecular techniques to decipher how the water conditions affect algal blooms and the bloom conditions and how other microorganisms in the water interact with cyanobacteria and impact bloom conditions.

That analysis will help better understand what triggers the toxin gene production of cyanobacteria.

Seo is focused on mitigation and the treatment method for toxin removal. His lab is working on biological degradation of cyanobacteria and their toxins using the naturally occurring bacteria and viruses from the lake and NSF-approved chemical treatments.

“Once we detect the harmful algal bloom, we will try to reduce the algal bloom in early stages, using bacteria and algicide treatments of the cyanobacteria and their toxin directly in the lake to control the toxin from spreading,” Seo said. “We are collaborating with microbiologists at the Ohio State University who have isolated different viruses of the cyanobacteria, and we are evaluating their effectiveness to control the harmful algal bloom.”

Seo says the goal is to introduce new techniques to mitigate the harmful algal blooms through early detection and work with water treatment plants to optimize and improve their treatment methods.


Reminder: Class of 2021 Commencement to be Celebrated in Person May 8

The Class of 2021 will walk across the stage in the Glass Bowl to celebrate receiving their degrees this weekend.

The University of Toledo will hold multiple in-person commencement ceremonies to celebrate graduates in person while also adhering to COVID-19 safety protocols.

UToledo spring commencement ceremonies will be held at 10 a.m. and 3 p.m. Saturday, May 8, in the Glass Bowl.

The 10 a.m. ceremony recognizes graduates from the colleges of Engineering; Health and Human Services; Nursing; and University College.

The 3 p.m. ceremony recognizes graduates from the colleges of Arts and Letters; the John B. and Lillian E. Neff College of Business and Innovation; Judith Herb College of Education; and Natural Sciences and Mathematics.

The commencement events commemorate 1,964 candidates for bachelor’s degrees, 703 candidates for master’s degrees, 52 candidates for associate’s degrees, 12 candidates for educational specialist and 45 candidates for graduate certificates.

Plus, 302 graduates from the Class of 2020 who earned their degrees during the coronavirus pandemic are scheduled to return to campus to participate in the May ceremonies.

Graduating students are split into groups for the separate ceremonies and guests are limited with tickets required for admission. All attendees will be required to wear face masks and keep at least 6 feet from others not in their household.

“We’re excited to have the opportunity to provide our graduates with an in-person celebration,” UToledo President Gregory Postel said. “Our Rockets continue to demonstrate focus, perseverance and strength through their academic success, despite the challenges presented by COVID-19 during the last year. We look forward to celebrating the Class of 2021’s achievements and resilience at our in-person spring commencement ceremonies.”

The ceremonies also will be streamed live online at utoledo.edu/commencement.

UToledo alumna Irma Olguin, Jr. will remotely deliver the keynote address at the ceremonies.

Irma Olguin, Jr.

Olguin is co-founder and chief executive officer of Bitwise Industries in Fresno, Calif. She graduated in 2004 from the UToledo College of Engineering with a bachelor’s degree in computer science and engineering and went on to blaze a trail of inclusivity for women and minorities in the tech industry.

In March, Bitwise Industries announced it is investing in Toledo. Olguin’s tech company plans to open a branch in in the Jefferson Center building, Toledo’s historic former post office, to provide paid apprenticeships to students from diverse and underserved communities to learn tech skills.

“Ms. Olguin is an outstanding UToledo alumna making an incredible impact on the world,” said Dr. Karen Bjorkman, provost and executive vice president for academic affairs. “We are pleased to welcome the entrepreneur as our commencement speaker to inspire our newest alumni as they receive their degrees.”

The College of Pharmacy and Pharmaceutical Sciences held its separate in-person ceremony last weekend.

College of Law Commencement is 10 a.m. Saturday, May 15, in Savage Arena.

College of Medicine and Life Sciences Commencement is 3 p.m. Friday, May 21, in Savage Arena.

And those receiving doctoral degrees will have the opportunity to participate in a separate hooding ceremony at 6 p.m. Friday, May 7, in Savage Arena.


NASA Selects Projects Led by UToledo Astronomers for James Webb Space Telescope’s First Observing Cycle

Astronomers at The University of Toledo were selected by NASA to lead five of the first research projects on the James Webb Space Telescope, a new infrared telescope scheduled to launch in October.

One of the projects is led by a UToledo graduate student.

“While it’s exciting for our program to have five accepted proposals in the first observing cycle of this highly competitive, next-generation space telescope, the real thrill came from Ph.D. Student Thomas Lai’s success with his proposal targeting a unique starburst galaxy,” said Dr. J.D. Smith, director of UToledo Ritter Astrophysical Research Center and professor of astronomy.

Students lead 8.7% of selected proposals, according to the Space Telescope Science Institute.

Thomas Lai

Lai, who is scheduled to graduate in May with a doctorate in physics and astronomy, is leading an international team of 10 other researchers on a project titled “How Do the Small Survive.” They will observe a galaxy called II Zw 40 that is roughly 33 million light years away from Earth and hosts one of the most intensive star-forming regions in the local universe.

“I feel extremely fortunate to have the opportunity to use this flagship NASA space observatory,” Lai said. “Using the power of the James Webb Space Telescope we will be able to study how dust behaves near the sites of intense star formation with unprecedented high spatial resolution. Ultimately, we would like to answer the questions on why and how small dust grains survive in the universe despite strong radiation fields produced by newly formed young stars.”

UToledo is ranked No. 6 among all institutions worldwide in terms of successful proposals for the first cycle of the James Webb Space Telescope.

From more than 1,000 submitted proposals, NASA selected 286 projects to address a wide variety of science areas. Proposals are split into eight different categories – planets, stars and galaxies, for example.

“Nearly 20% of the star time is going to UToledo because of our large programs in that category,” said Dr. Michael Cushing, professor of physics and astronomy and director of UToledo Ritter Planetarium. “Of the 740 hours awarded in the category of Stellar Physics and Stellar Types, 140 hours went to UToledo.”

Cushing is leading a project titled, “Bolometric Luminosities of Cool Brown Dwarfs: The Key to Their Effective Temperatures and the Mass Function.”

“The initial year of Webb’s observations will provide the first opportunity for a diverse range of scientists around the world to observe particular targets with NASA’s next great space observatory,” said Dr. Thomas Zurbuchen, associate administrator for the Science Mission Directorate at NASA. “The amazing science that will be shared with the global community will be audacious and profound.”

UToledo-led projects also include:

  • “Vanishing Act: PAHs and Heavy Element Abundance in M101” by Smith;
  • “Come Out, Come Out, Wherever You Are: Seeking All the Massive Young Clusters Hidden in the Antennae” by Dr. Rupali Chandar, professor of astronomy; and
  • “Investigating Protostellar Accretion Across the Mass Spectrum” by Dr. Tom Megeath, professor of physics and astronomy.

“The James Webb Space Telescope is going to completely transform our understanding of galaxies, star formation and ultra-cool stars, and UToledo astrophysicists have real strengths in these research areas,” Smith said. “Our group is also deeply experienced in exploiting JWST’s long infrared wavelengths of light to study the cold, dust-veiled universe. Now all our eyes are on the space telescope’s Halloween launch later this year.”

Webb will begin observing the universe in 2022 after the spacecraft unfolds, travels a million miles and checks the functioning of all of its instruments.

“We are opening the infrared treasure chest, and surprises are guaranteed,” said Dr. John C. Mather, senior project scientist for the Webb mission and senior astrophysicist at NASA’s Goddard Space Flight Center in Greenbelt, Md. “How did the universe make galaxies, stars, black holes and planets, and our own very special little Earth? I don’t know yet, but we are getting closer every day.”

General observer time with Webb is extremely competitive. As a result, the proposal selection process conducted by the Telescope Allocation Committee is both rigorous and meticulous. The committee was comprised of nearly 200 members of the worldwide astronomical community who were assigned to 19 different panels covering broad scientific topics.

Using dual-anonymous review, where the identities of the proposing investigator and team were concealed, the scientific merit of each proposal was evaluated and ranked. The final, ranked list of selected proposals was presented to the Space Telescope Science Institute’s Director, Dr. Kenneth Sembach, for review and approval.

“The first observing cycle with a new observatory is always special, especially one as powerful and highly anticipated as Webb. We had an incredibly interesting couple of weeks of intense proposal reviews during which the reviewers did a great job of sorting through and ranking all the possible science cases proposed. I commend them for their hard work, especially under pandemic conditions,” said Sembach. “I’m very pleased to be able to approve such a strong science program for the observatory. These observations are going to provide stunning views of the universe and lead us in new investigative directions that will set the stage for decades of research.”